Antimicrobial Study of Oil and Stem Bark Extracts of Pentaclethra Macrophylla Benth on Six Selected Pathogens
DOI:
https://doi.org/10.18034/mjmbr.v3i1.399Keywords:
Pentaclethra macrophylla benth, antimicrobial, clinical isolatesAbstract
The antimicrobial activity of oil and stem bark extracts of pentaclethra macrophylla benth was determined against staphylococcus aureus, streptococcus pneumonia, Eschericia coli, Haemophilus influenza, α-Haemolytic Streptococcus and Yeast, using hole diffusion method. The results revealed that the most inhibitory zone (25.0mm) was recorded in hexane oil extract against staphylococcus aureus and α-Haemolytic Streptococcus. The minimum inhibitory concentration (MIC) of the oil extract ranges between 7.8125-62.5mg/ml on all the test organisms and aqueous stem bark extract inhibited only Eschericia coli with minimum, inhibitory concentration (MIC) of 62.5mg/ml. However, the oil extract possessed more antimicrobial activity than the stem bark extract. These findings lend more knowledge to the use of pentaclethra macrophylla benth for medicinal purposes.
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Akah, P.A., Aguwa, C.N., and Agu, R.U. (1999). Studies on the andiarrhoeal properties of Pentaclathramacrophylla leaf extracts. African Journal of Traditional complementary and Alternative Mediumes, Vol. 3, 44-53.
Cousin D. and Huffman, M.A (2002). Medicinal Properties in thte Diet of Gorrilas, and Ethnopharmacological Evaluation. African studies Monographs, 23 (2); 65-89.
http://database.prota.org/PROTAhtml/Pentaclethra%20macrophylla_En.htm
Ibekwe, V.I., Ugbochi, K.C and Anyanwu, B.N. (2002). The prevalence of Penicillin Resistant in Organisms that cause sexually transmitted disease in Port-Harcourt Nigeria. Int. J. Environmental Health Res:10:251-255.
Kamanzi, Aundehou, K., Kone, M., terreaux, C., Traore, D., Hostettman, K, and Dosso, M. (2002). Evaluation of the Antimicrobial potential of Medicinal Plants from Ivory Coast. Phytother Res:497-502.
Ladipo, d.O., Kang, B.T., and Swift, M.J. (1993). Nodulation in PentaclethramacrophyllaBenth; A multi-purpose tree with potential for agroforestry in the humid lowlands of West Africa, Nitrogen Fixing Tree Reports 11:104-105.
Montefioure, D., Rotimi, V.O., and Deyemi-Doro F.A.B. (1989). The problem of bacteria Resistance to Anti-biotic among strains isolated from Hospital Patients in Lagos and Ibadan, Nigeria. J.Antimicrobial Chemotherapy.23:641-651.
Oboh, G., (2007) Pentaclethra macrophylla Benth. In: van der Vossen, H.A.M. & Mkamilo, G.S. (Editors). PROTA 14: Vegetable oils/Oléagineux. [CD-Rom]. PROTA, Wageningen, Netherlands.
Odoemelain, S.A., (2005). Proxinatecompostition and selected physiochemical properties of the seeds of Oil Bean. Pakistan J. Nutri 4(6) 382-383.
Okorie, C.C., oparaocha, E.N.T., Adewunmi, O., Iwalewa, E.o., and Omodara, S.K. (2006). African Journal of Traditional, Complementary and Alternative medicine Vol. 3 pp44-53.
Olaitan, J.o., Kareem S.O., and Dada, S.O., (2009). Antimicrobial Potency of Pentaclethra Macrophyll seed Extract on seven selected pathogens. African Journal of Biomedical Research Vol. 12 No. 2 Pp 141-144.
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