The Biological Effectiveness and Medical Significance of Far Infrared Radiation (FIR)

Authors

  • Li-Chi Lin GHI FU Technology Co., Ltd.
  • Yi-Ying Lin Green Luminant International Co., Ltd.

DOI:

https://doi.org/10.18034/mjmbr.v8i1.564

Keywords:

Far infrared radiation (FIR), Infra-red, Electromagnetic waves, Biological effectiveness, Medical significance

Abstract

The electromagnetic waves constitute different wavelengths of light from which Far infrared (FIR) is beneficial for living cells. Extensive studies and trials have been conducted over the last two decades in multidimensional biological domains to identify its unlimited health benefits. FIR radiations improve the microcirculation of the human body, stimulate cell growth, penetrate through skin tissues non-invasively, create intramolecular vibrations create an overall healthy metabolism, which ultimately affects overall improved cardiac and metabolic activity. This phenomenon is used to explore different pathological conditions to identify their significance in the medical field. In this review, we explored the biological effectiveness and the medical significance of Far infrared radiation (FIR) in murine melanoma Cell Growth, Lymphedema, airborne viruses, Cardiac diseases, Wound healing and burns, Autonomic Activities, Hemodialysis, Allergic Rhinitis, Aesthetic medicine, textiles, and other domains such as obesity and gut microbiota.

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Author Biographies

  • Li-Chi Lin, GHI FU Technology Co., Ltd.

    CEO, GHI FU Technology Co., Ltd., TAIWAN

  • Yi-Ying Lin, Green Luminant International Co., Ltd.

    Founder, Green Luminant International Co., Ltd., TAIWAN

References

Barolet, D., Christiaens, F., Hamblin, M. R. (2016). Infrared and skin: Friend or foe. Journal of Photochemistry and Photobiology B: Biology, 155, 78-85, https://doi.org/10.1016/j.jphotobiol.2015.12.014

Basuk, M. (2018). Improving the Performance of Human Body with Far Infra-Red Rays Reflecting Textiles. Current Trends in Fashion Technology & Textile Engineering, 4(3), 51-59.

Beever, R. (2009). Far-infrared saunas for treatment of cardiovascular risk factors: summary of published evidence. Can Fam Physician, 55(7), 691-696. https://pubmed.ncbi.nlm.nih.gov/19602651/

Biro, S., Masuda, A., Kihara, T., & Tei, C. (2003). Clinical Implications of Thermal Therapy in Lifestyle-Related Diseases. Experimental Biology and Medicine, 228(10), 1245–1249. https://doi.org/10.1177/153537020322801023

Bontemps, B., Gruet, M., Vercruyssen, F., Louis, J. (2021). Utilisation of far infrared-emitting garments for optimising performance and recovery in sport: Real potential or new fad? A systematic review. PLOS ONE 16(5), 1-15, https://doi.org/10.1371/journal.pone.0251282

Bontemps, B., Gruet, M., Vercruyssen, F., Louis, J. (2021). Utilisation of far infrared-emitting garments for optimising performance and recovery in sport: Real potential or new fad? A systematic review. PLOS ONE, 16(5), e0251282. https://doi.org/10.1371/journal.pone.0251282

Cho, H. K., Jeong, Y. M., Lee, H. S., Lee, Y. J., & Hwang, S. H. (2015). Efficacy of Endonasal Phototherapy for Relieving the Symptoms of Allergic Rhinitis: Meta-Analysis. American Journal of Rhinology & Allergy, 29(4), 283–291. https://doi.org/10.2500/ajra.2015.29.4190

Cristiano, L. (2019). Use of infrared as a complementary treatment approach in medicine and aesthetic medicine. Asp Biomed Clin Case Rep. 2(2), 77-81. https://doi.org/10.36502/2019/ASJBCCR.6164

Farooq, A. S., Peng, Z. (2021). Fundamentals, materials and strategies for personal thermal management by next-generation textiles. Composites Part A: Applied Science and Manufacturing, 142, 106249. https://doi.org/10.1016/j.compositesa.2020.106249

Henderson, T. A. (2016). Multi-watt near-infrared light therapy as a neuroregenerative treatment for traumatic brain injury. Neural Regen Res, 11(4), 563-565. https://doi.org/10.4103/1673-5374.180737

Hsu, YH., Chen, YW., Cheng, CY., Lee, SL., Chiu, TH., & Chen, CH. (2019). Detecting the limits of the biological effects of far-infrared radiation on epithelial cells. Scientific Reports, 9, 1-9, https://doi.org/10.1038/s41598-019-48187-0

Hu, J., Choo, H. J., & Ma, S. (2011). Infrared heat treatment reduces food intake and modifies expressions of TRPV3-POMC in the dorsal medulla of obesity prone rats. International Journal of Hyperthermia, 27(7), 708-716, https://doi.org/10.3109/02656736.2011.601283

Hu, KH., & Li, WT. (2007). Clinical effects of far-infrared therapy in patients with allergic rhinitis. Annu Int Conf IEEE Eng Med Biol Soc., 1479-1482. https://doi.org/10.1109/iembs.2007.4352580

Khan, I., Pathan, S., Li, X. A., Leong, W. K., Liao, W. L., Wong, V., Hsiao, W. L. W. (2020). Far infrared radiation induces changes in gut microbiota and activates GPCRs in mice. Journal of Advanced Research, 22, 145-152, https://doi.org/10.1016/j.jare.2019.12.003

Kokura, S., Adachi, S., Manabe, E., Mizushima, K., Hattori, T., Okuda, T., Nakabe, N., Handa, O., Takagi, T., Naito, Y., Yoshida, N., & Yoshikawa, T. (2007). Whole body hyperthermia improves obesity-induced insulin resistance in diabetic mice. International Journal of Hyperthermia, 23(3), 259-265, https://doi.org/10.1080/02656730601176824

Leung, TK., Chan, CF., Lai, PS., Yang, CH., Hsu, CY., Lin, YS. (2012). Inhibitory Effects of Far-Infrared Irradiation Generated by Ceramic Material on Murine Melanoma Cell Growth. International Journal of Photoenergy, Volume 2012, Article ID 646845. https://doi.org/10.1155/2012/646845

Li, E., Lu, J., Dong, S., Zhang, M., Cen, S., Li, L. and Huang, W. (2020). Instability of Nucleic Acids in Airborne Microorganisms under Far Infrared Radiation. Health, 12, 998-1007. https://doi.org/10.4236/health.2020.128074

Li, K., Zhang, Z., Liu, N. F., Sadigh, P., Evans, V. J., Zhou, H., Gao, W., and Zhang, Y. X. (2018). Far-Infrared Radiation Thermotherapy Improves Tissue Fibrosis in Chronic Extremity Lymphedema. Lymphatic Research and Biology, 16(3), 248-257. https://doi.org/10.1089/lrb.2016.0057

Lin, CC., Yang, WC., Chen, MC., Liu, WS., Yang, CY., Lee, PC. (2013). Effect of far infrared therapy on arteriovenous fistula maturation: an open-label randomized controlled trial. Am J Kidney Dis., 62(2), 304-311. https://doi.org/10.1053/j.ajkd.2013.01.015

Lin, Y.-H., & Li, T.-S. (2017). The Application of Far-Infrared in the Treatment of Wound Healing: A Short Evidence-Based Analysis. Journal of Evidence-Based Complementary & Alternative Medicine, 22(1), 186–188. https://doi.org/10.1177/2156587215623436

Masuda, A., Kihara, T., Fukudome, T., Shinsato, T., Minagoe, S., Tei, C. (2005). The effects of repeated thermal therapy for two patients with chronic fatigue syndrome. J Psychosom Res, 58(4), 383-387.

Masuda, A., Koga, Y., Hattanmura, M., Minagoe, S., Tei, C. (2005). The effects of repeated thermal therapy for patients with chronic pain. Psychother Psychosom, 74(5), 288-294.

Peng, Y., & Cui, Y. (2020). Advanced textiles for personal thermal management and energy, Joule, 4(4), 724-742. https://doi.org/10.1016/j.joule.2020.02.011

Putowski, M., Piróg, M., Podgórniak, M., Padała, O., Sadowska, M., Bazylevycz, A., & Wdowiak, A. (2016). The use of electromagnetic radiation in the physiotherapy. Eur J Med Technol, 2(11), 53-58.

Shui, S., Wang, X., Chiang, J. Y., & Zheng, L. (2015). RETRACTED: Far-infrared therapy for cardiovascular, autoimmune, and other chronic health problems: A systematic review. Experimental Biology and Medicine, 240(10), 1257–1265. https://doi.org/10.1177/1535370215573391

Simmons, J. D., Kahn, S. A., Vickers, A. L., Crockett, E. S., Whitehead, J. D., Krecker, A. K., Lee, YL., Miller, A. N., Patterson, S. B., Richards, W. O., Wagner, W. W. Jr. (2018). Early Assessment of Burn Depth with Far Infrared Time-Lapse Thermography. J Am Coll Surg., 226(4), 687-693. https://doi.org/10.1016/j.jamcollsurg.2017.12.051

Su, LH., Wu, KD., Lee, LS., Wang, H, Liu, CF. (2009). Effects of far infrared acupoint stimulation on autonomic activity and quality of life in hemodialysis patients. The American Journal of Chinese Medicine, 37(2), 215-226. https://doi.org/10.1142/S0192415X09006783

Suwandee, S. & Yupapin, P. P. (2014). Gemstone Property Studies for Minerals Based Cosmetics and Beauty Applications, Life Science Journal, 11(11), 871-873, https://doi.org/10.1016/j.joule.2020.02.011

Toyokawa, H., Matsui, Y., Uhara, J., Tsuchiya, H., Teshima, S., Nakanishi, H., Kwon, A.-H., Azuma, Y., Nagaoka, T., Ogawa, T., & Kamiyama, Y. (2003). Promotive Effects of Far-Infrared Ray on Full-Thickness Skin Wound Healing in Rats. Experimental Biology and Medicine, 228(6), 724–729. https://doi.org/10.1177/153537020322800612

Tsai, SR., Hamblin, M. R. (2017). Biological effects and medical applications of infrared radiation. Journal of Photochemistry and Photobiology B: Biology, Volume 170, 197-207, https://doi.org/10.1016/j.jphotobiol.2017.04.014

Tsai, WC., Chiang, WH., Wu, CH., Li, YC., Campbell, M., Huang, PH., Lin, MW., Lin, CH., Cheng, SM., Chang, PC., Cheng, CC. (2020). miR-548aq-3p is a novel target of Far infrared radiation which predicts coronary artery disease endothelial colony forming cell responsiveness. Scientific Reports, 10, 1-17. https://doi.org/10.1038/s41598-020-63311-1

Vatansever, F. & Hamblin, M. (2012). Far infrared radiation (FIR): Its biological effects and medical applications. Photonics & Lasers in Medicine, 1(4), 255-266. https://doi.org/10.1515/plm-2012-0034

Yamashita, K. (2012). The Effects of the Far-Infrared Ray (FIR) Energy Radiation on Living Body, Blood Cell - An Overview of Studies in Hematology. Blood Cell - An Overview of Studies in Hematology,, https://doi.org/10.5772/36005

Yang, CC., Lin, GM., Wang, JH., Chu, HC., Wu, HT., Chen, JJ., Sun, CK. (2017). Effects of Combined Far-Infrared Radiation and Acupuncture at ST36 on Peripheral Blood Perfusion and Autonomic Activities. Evidence-Based Complementary and Alternative Medicine, Volume 2017, Article ID 1947315. https://doi.org/10.1155/2017/1947315

Yu, SY., Chiu, JH., Yang, SD., Hsu, YC., Lui, WY., Wu, CW. (2006). Biological effect of far-infrared therapy on increasing skin microcirculation in rats. Photodermatol Photoimmunol Photomed, 22, 78-86.

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Published

2021-06-20

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Section

Peer-reviewed Article

How to Cite

Lin, L.-C., & Lin, Y.-Y. (2021). The Biological Effectiveness and Medical Significance of Far Infrared Radiation (FIR). Malaysian Journal of Medical and Biological Research, 8(1), 41-46. https://doi.org/10.18034/mjmbr.v8i1.564