The Pattern of Distribution of ABO Blood Groups in Kaduna Metropolis, Nigeria
DOI:
https://doi.org/10.18034/mjmbr.v6i1.472Keywords:
ABO blood group, antigen, Hardy-Weinberg, allelic frequency, genotypic frequency, distribution, phenotypic frequencyAbstract
The study was undertaken to assess the distribution of the ABO blood groups in Kaduna metropolis, Nigeria. Blood group types of forty-three thousand, nine hundred and nineteen (43,919) people were collected from eight different hospitals in Kaduna metropolis over a period of four years. These hospitals are easily accessible by all groups and classes of people because of their location. Phenotypic and allelic frequencies were determined to understand the distribution pattern of the ABO blood groups. A chi-square test was carried out to test whether the population was in Hardy-Weinberg equilibrium. The O blood group occurred with the highest frequency (44.13%), while the AB blood group had the lowest occurrence of 3.98%. Blood group A was more predominant (29.12%) than B blood group (22.77%). The O allele had the highest allelic frequency (0.67), while the A and B alleles were lower (0.19 and 0.14 respectively). The ABO blood group system was found to be in Hardy-Weinberg equilibrium.
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Anifowoshe, A.T.; Owolodun, O.A.; Akinseye, K.M.; Iyiola, O.A. and Oyeyemi, B.F. (2016). Gene frequencies in ABO and Rh blood groups in Nigeria: A review. Egyptian Journal of Medical Human Genetics. http://www.sciencedirect.com/science/article/pii/S111086301630074X.
Beckman, L. (2008). Racial and ethnic distribution of ABO blood types. Physical Anthropology and Population Genetics. As revised by BloodBook.com http://www.bloodbook.com/world-abo.html. (Accessed 03 February 2017)
Musa, A.U., Ndakotsu, M.A., Abdul-Aziz H., Kilishi A., Aliyu I. (2015). “Distribution of ABO and Rhesus blood group systems among blood donors in Sokoto North-western Nigeria.” Journal of Applied Haematology. Vol. 6 (3): 136-138
O’Neil, D. (2012). “Distribution of Blood Types.” Modern human variation distribution of blood types.htm. http://anthro.palomar.edu/vary/vary_3.htm Copyright © 1998-2012
Odokuma, E. I, Okolo, A. C, and P. C. Aloamaka, P. C. (2007). “Distribution of ABO and rhesus blood groups in Abraka, Delta State, Nigeria.” Nigerian Journal of Physiological Sciences Vol. 22 (1-2): 89-91. Available online/abstracted at http://www.biolineinternational.org.br/njps
Pughikumo, D.T, Onyebuagu, P.C,and Pughikumo O.C. (2014). A Preliminary Study of Blood Groups among Students in Bayelsa State. International Journal of Basic, Applied and Innovative Research Vol 3(1): 19 – 22. Available online www.arpjournals.com; www.antrescentpub.com.
Tamarin, R. (1991). “Principles of Genetics.” Win C. Brown publishers. 3rd Edition. W. B. Saunders Company, Toronto.
The-Editors-of-Encyclopedia-Britannica (2009). “ABO blood group systems.” Encyclopedia Britannica Inc.htm. https://www.britannica.com/science/ABO-blood-group-system. (Accessed 13 February 2017)
Yamamoto F, Clausen H, White T, Marken J, Hakomori S. (1990). “Molecular genetic basis of the histo-blood group ABO system.” Nature. Vol 345:229–33.
Zerihun T. and Bekele S. (2016). “Pattern of ABO and Rhesus Blood Groups Distribution of Five Years Survey in Jimma Town Blood Bank, South West Ethiopia.” Journal of Health Education Research & Development. http://www.esciencecentral.org/journals/pattern-of-abo-and-rhesus-blood-groups-distribution. (Accessed 13 February 2017).
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